Food ARA Arachidonic Acid CAS 506-32-1 API Active Pharmaceutical Ingredients

Model Number : HMHT0048
Other Names : (5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid5,8,11,14-Eicosatetraenoic acid, (all-Z)-5,8,11,14-ALL-CIS-EICOSATETRAENOIC ACID5,8,11,14-EICOSATETRENOIC ACIDArachidonate

Properties of arachidonic acid (506-32-1):
1. This product is a n6 polyunsaturated fatty acid. Those with AA content above 40% are pale yellow liquids, and those with AA content below 25% are generally white granular crystals. Good thermal stability under anaerobic conditions (60°C, 40 days, peroxide value 1.5, odorless).
2. It is soluble in n-hexane, ethanol, etc., and a small amount is soluble in water at 37°C. The ethyl ester of AA is a colorless and transparent liquid.
3. Arachidonic acid (AA) is the metabolic hub of n6 fatty acids in the human body. All n6 fatty acids such as linoleic acid, γ-linolenic acid, and di-homo-γ-linolenic acid will eventually be chain lengthened and desaturated. The reaction is transformed into AA, and then transformed from AA into a series of important physiologically active substances (prostaglandins, leukotrienes, etc.). These biological reactions are widespread in animals. Therefore, AA is widely present in animal tissues. Various animal fats, such as lard, beef tallow, mutton fat, etc., contain a small amount of AA, and a certain amount of AA is also contained in various muscle tissues. However, it is often difficult to meet the needs of specific populations such as infants and young children. AA is found in certain mosses, seaweeds and other plants, as well as in the adrenal glands, liver and herring of pigs and cattle. Under the catalysis of different enzyme systems in the organism, important active substances such as prostaglandins, thromboxanes and leukotrienes are produced. There are four double bonds in the molecule, of which the first double bond starts on the 6th carbon atom from the methyl end and belongs to the omega-6 type unsaturated fatty acid. AA is a light yellow oily liquid. Soluble in organic solvents such as ethanol, acetone and benzene. The mp is about 49°C; the bp 169-171°C/19.998Pa; the flash point is greater than 110°C; the refractive index is 1.4824; the density is 0.922g/ml; the iodine value is 333.4. There are four active methine groups in the molecule, which can easily react with oxygen to generate free radicals. In 21% KOH ethylene glycol, the UV absorption spectrum of isomerization at 180°C for 15 min has characteristic absorption peaks at 233nm, 268nm, 315nm, and 346nm.

FAO/WHO: 60rag/(kg body weight?d) for infants and young children.
GB 2760 2002: Infant formula milk powder 1.6～2.6g/kg. Infant formula milk powder 0.09%～0.15% [% of fatty acid; refers to arachidonic acid single cell oil (ARASCO)]