High Purity Sodium Chloroacetate C2H2ClNaO2 Specialist Chemical Intermediate Reagent for Organic Synthesis

Sodium Chloroacetate (SMCA) Basic Chemical Information

Sodium Chloroacetate (also known as Chloro‑aceticacisodiumsalt) has the formula C₂H₂ClNaO₂ and CAS No. 3926‑62‑3 fishersci.com+11en.wikipedia.org+11tera.org+11. It appears as a white, hygroscopic crystalline powder, soluble in water (~440–820 g/L at 20 °C) and many organic solvents de.wikipedia.org+2chemicalbook.com+2atamanchemicals.com+2. Its density is ~1.4–1.87 g/cm³ with melting/decomposition above 150 °C cdhfinechemical.com+10en.wikipedia.org+10chemicalbook.com+10.

2. Preparation and SMCA Synthesis Pathways

Sodium Monochloroacetate is manufactured by neutralizing chloroacetic acid with sodium carbonate or sodium hydroxide:

2 CH₂ClCOOH + Na₂CO₃ → 2 CH₂ClCOONa + H₂O + CO₂ echa.europa.eu+4zh.wikipedia.org+4de.wikipedia.org+4.

Alternatively, sodium hydroxide can be used, though carbonate is preferred industrially for cost‑effectiveness chemspider.com+1mubychem.com+1.

3. Chemical Reactivity and Applications

Sodium Chloroacetate acts as a potent alkylating agent, introducing the –CH₂CO₂⁻ group into nucleophiles . Common applications include:

• Synthesis of carboxymethyl cellulose (CMC) used in adhesives, textiles cdhfinechemical.com+4en.wikipedia.org+4thermofisher.com+4.

• As precursor to herbicides (e.g., dimethoate), pharmaceuticals, dyes, polymers, thioglycolic acid, cyanoacetate, malonic acid en.wikipedia.org+1atamanchemicals.com+1.

• As reagent in fine‑chemical and laboratory syntheses in Organic Syntheses en.wikipedia.org.

4. Physical Properties and Safety Profile

Sodium Chloroacetate is non‑flammable but decomposes to corrosive/toxic gases when heated atamanchemicals.com+15cameochemicals.noaa.gov+15mubychem.com+15. It is moderately toxic orally and via inhalation, causes skin irritation, and is very toxic to aquatic life pubchem.ncbi.nlm.nih.gov+2assets.thermofisher.com+2thermofisher.com+2.

5. Environmental Impact and Handling

Due to its high solubility and mobility in water, SMCA can spread in soil and aquatic systems; it is toxic to aquatic organisms and should not enter drains assets.thermofisher.com+1atamanchemicals.com+1. Hazard handling protocols include spill containment using absorbents and protective equipment under adequate ventilation cdhfinechemical.com.

6. Proper Storage and Transport

Store Sodium Chloroacetate in a cool, dry, well‑ventilated area in tightly sealed containers, away from oxidizers and heat sources fishersci.com+2mubychem.com+2cameochemicals.noaa.gov+2. It is classified as UN 2659, Hazard Class 6.1, Packing Group III for transport under DOT/IATA/IMDG regulations atamanchemicals.com+5fishersci.com+5fishersci.com+5.

7. Where to Find High‑Purity Sodium Chloroacetate

For reagent and industrial grades SMCA, visit HighMountainChem’s Sodium Chloroacetate product page at https://highmountainchem.com/ (internal link) to explore purity grades, certifications, technical documents, and ordering details.

8. SEO‑Focused Summary

This overview equips researchers and purchasers with essential data on SMCA, covering chemical nature, synthesis routes, diverse uses, and critical safety and environmental guidelines. Incorporating terms like Sodium Chloroacetate, SMCA, Chloro‑aceticacisodiumsalt, plus references to CAS 3926‑62‑3 and major applications ensures alignment with SEO best practices.

References

• PubChem and ChemSpider for structural and property data fishersci.ca+2chemicalbook.com+2atamanchemicals.com+2chemspider.com+1de.wikipedia.org+1

• Wikipedia and NOAA for uses, hazards, reactivity diesel-additive.com+11en.wikipedia.org+11cameochemicals.noaa.gov+11

• ATAMAN and ECHA for detailed usage examples and industrial relevance mubychem.com+15atamanchemicals.com+15echa.europa.eu+15

• SDS sources for ecological toxicity, handling, hazard classification fishersci.com

Product Parameters

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