Sodium Chloroacetate (SMCA) (C₂H₂ClNaO₂, CAS 3926‑62‑3) is the sodium salt of Monochloroacetic Acid (MCA) (C₂H₃ClO₂, CAS 79‑11‑8) cognitivemarketresearch.com+5atamanchemicals.com+5benchchem.com+5. SMCA is a white, water‑soluble crystalline powder, while MCA is a corrosive, colorless or white crystalline acid. SMCA is less corrosive and safer to handle, making it more suitable for industrial processes and transportation atamanchemicals.com+1chemicalbook.com+1.
Both compounds act as potent alkylating agents, introducing the –CH₂CO₂⁻ or –CH₂CO₂H groups. However, SMCA is often preferred over MCA for organic synthesis, CMC production, and agrochemical manufacturing due to its lower hazard profile and easier regulatory handling . Despite this, MCA remains essential when a strong acid is required for specific reactions.
SMCA is moderately toxic (oral LD₅₀ 76–580 mg/kg in rodents), causes skin/eye irritation, and is very toxic to aquatic life sciencedirect.com+11ecetoc.org+11patents.google.com+11.
MCA is highly corrosive, significantly more toxic (oral LD₅₀ ~76 mg/kg), causing severe burns and requiring stringent handling procedures .
Both are mobile and have aquatic toxicity, but SMCA’s salt form makes environmental monitoring easier and less hazardous in industrial settings .
SMCA is classified under UN 2659, Hazard Class 6.1, Packing Group III—easier to ship internationally due to lower corrosion risk ecetoc.org+2fishersci.ie+2atamanchemicals.com+2.
MCA, being a corrosive acid, often falls under more stringent dangerous goods categories like Class 8, requiring more rigorous handling, labeling, and transport packaging .
Industries favor SMCA because it delivers the reactive alkylating properties of MCA without severe corrosion risks. According to Ataman Chemicals, SMCA is "less corrosive as it is a natural product so handling is safer and less hazardous" compared to MCA atamanchemicals.com. This makes it a safer, more cost‑effective alternative in large-scale production environments.
Curious about SMCA purity grades and specifications? Visit HighMountainChem’s Sodium Chloroacetate page to explore industrial and reagent grades, detailed tech specs, and storage recommendations:
https://highmountainchem.com/sodium-chloroacetate-cas-3926-62-3/
Packaging Types
25kg/ drum or as per customers ' requirements .
Transport/Storage Information
Store in a sealed nitrogen atmosphere , in a cool and dry place , and keep it away from moisture .
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