Sodium Chloroacetate (C₂H₂ClNaO₂, CAS 3926‑62‑3) rapidly metabolizes to monochloroacetic acid (MCA) after ingestion. In rats, oral exposure leads to liver and kidney accumulation via metabolites like thiodiacetic and glycolic acids benchchem.com+4tera.org+4highmountainco.com+4. This highlights the compound’s systemic distribution and organ-specific impacts.
Oral LD₅₀ values range from 76–580 mg/kg in rodents, indicating moderate acute toxicity .
Inhalation and dermal data are limited, but Fisher’s SDS reports it may be fatal if absorbed through skin or inhaled pubchem.ncbi.nlm.nih.gov.
Exposure symptoms include skin corrosion, respiratory distress, convulsions, nausea, and abdominal pain tera.org+14highmountainco.com+14pubchem.ncbi.nlm.nih.gov+14.
Long-term exposure may impair liver and renal function, damage fertility, and harm fetal development chemicalsafety.ilo.org+2ecetoc.org+2echa.europa.eu+2.
A 90-day rat study identified a LOAEL at 15 mg/kg/day, suggesting caution with repeated exposure pubchem.ncbi.nlm.nih.gov+12tera.org+12ecetoc.org+12.
The WEEL guideline suggests a TWA of 0.5 ppm (2.5 mg/m³) over 8 hours highmountainco.com+7tera.org+7nj.gov+7.
The German MAK (inhalable) limit is 2 mg/m³, also noting significant skin absorption risk chemicalsafety.ilo.org+1highmountainco.com+1.
Acute exposure guidelines (e.g., AEGL-1) range from 0.83 ppm (12ppm short-term) elchemy-website.s3.ap-south-1.amazonaws.com+1highmountainco.com+1.
Ingestion: Rinse mouth; do not induce vomiting; seek medical care hpvchemicals.oecd.org+2highmountainco.com+2fishersci.co.uk+2.
Skin contact: Rinse with water; remove contaminated clothing; consult a physician .
Inhalation: Move to fresh air; get medical attention if symptoms persist highmountainco.com.
Eyes: Flush with water for 15+ minutes; seek immediate medical attention.
Acute Tox. 3 (H301): Toxic if swallowed
Skin Irrit. 2 (H315)
Eye Irrit. 2 (H319)
Aquatic Acute 1 (H400) – very toxic to aquatic life downloads.regulations.gov+12fishersci.co.uk+12canada.ca+12
UN 2659, Hazard Class 6.1 (Poisonous), Packing Group III echa.europa.eu+3hpvchemicals.oecd.org+3highmountainco.com+3
Use local exhaust or fume hoods when handling powders or solutions.
PPE: respirator (NIOSH-approved dust/mist), chemical-resistant gloves, goggles, lab coat or coveralls .
Conduct air monitoring; perform routine medical check-ups if use is sustained.
For information on technical-grade and analytical-grade Sodium Chloroacetate, including safety datasheets and packaging, visit HighMountainChem’s product page:
https://highmountainchem.com/sodium-chloroacetate-cas-3926-62-3/
Packaging Types
25kg/ drum or as per customers ' requirements .
Transport/Storage Information
Sealed and stored in a dry place.
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