Sodium Chloroacetate, also known as Sodium Monochloroacetate or Chloro‑aceticacisodiumsalt, has chemical formula C₂H₂ClNaO₂ and CAS number 3926‑62‑3 zh.wikipedia.org+14en.wikipedia.org+14highmountainco.com+14. It is a white crystalline powder, highly soluble in water (85–820 g/L at 20 °C) and some organic solvents sitem.herts.ac.uk+2chemicalbook.com+2highmountainco.com+2.
SMCA is industrially produced by neutralizing chloroacetic acid with sodium carbonate:
2 CH₂ClCOOH + Na₂CO₃ → 2 CH₂ClCOONa + H₂O + CO₂ cameochemicals.noaa.gov+15chemicalbook.com+15highmountainco.com+15zh.wikipedia.org.
This route is favored for cost efficiency over sodium hydroxide, though both are used.
Sodium Chloroacetate serves as a powerful alkylating agent, introducing the –CH₂CO₂⁻ function into various molecules . Its applications include:
Synthesizing carboxymethylcellulose (CMC) used in adhesives, textiles, food en.wikipedia.org.
As precursor for herbicides (dimethoate), pharmaceuticals, dyes, thioglycolic acid, cyanoacetate, malonic acid fishersci.com+11en.wikipedia.org+11zh.wikipedia.org+11.
Acting as surfactant or acid catalyst, cleaning agent and reagent in organic synthesis highmountainco.com.
SMCA is non-flammable but decomposes above ~150 °C, releasing corrosive/toxic gases highmountainco.com+2chemicalsafety.ilo.org+2cameochemicals.noaa.gov+2. Density is ~1.40 g/cm³ (25 °C) tera.org+9en.wikipedia.org+9pubchem.ncbi.nlm.nih.gov+9.
Acute hazards include skin and eye irritation, toxicity via ingestion or inhalation, and it is classified as very toxic to aquatic life chemicalbook.com+2lobachemie.com+2fishersci.com+2.
GHS hazard statements include:
H301: Toxic if swallowed
H315: Causes skin irritation
H319: Causes serious eye irritation
H332: Harmful if inhaled
H402: Harmful to aquatic life highmountainco.com+5mubychem.com+5merckmillipore.com+5.
To minimize risks:
Store in cool, dry, ventilated areas, sealed containers, away from oxidizers or moisture .
Use PPE—gloves, goggles, protective clothing, respirators in poor ventilation .
In case of spills, avoid dust, contain with inert absorbent, and prevent release into waterways .
SMCA is water-soluble and likely mobile in the environment exsyncorp.com. It is classified as very toxic to aquatic organisms, may cause long-term ecological effects, and should not enter drains .
Risk to algae is particularly high (EC₅₀ ≈ 0.009 mg/L) zh.wikipedia.org+5sitem.herts.ac.uk+5highmountainco.com+5.
SMCA is regulated globally—classified as UN 2659, hazard class 6.1, packing group III for transportation (DOT/IATA/IMDG) cameochemicals.noaa.gov+4fishersci.com+4sitem.herts.ac.uk+4.
It is regulated under Management of Chemicals directives for GHS hazard labeling and workplace exposure limits (e.g., WEEL TWA ≤ 0.5 ppm) tera.org.
For high-quality Sodium Chloroacetate (SMCA) in various grades and batch sizes, see the internal product page on HighMountainChem:
https://highmountainchem.com/sodium-chloroacetate-cas-3926-62-3/
Product Parameters
Product name
|
L-Lysine Hcl
|
Specification
|
99%
|
Appearance
|
White powder
|
Molecular Formula
|
C6H15ClN2O2
|
Test Method
|
HPLC
|
Molecular Weight
|
182.65
|
CAS
|
657-27-2
|
Odor
|
Characteristic
|
MOQ
|
1KG
|
Wuxi High Mountain Hi-tech Development Co., Ltd is a professional industrial company engaged in special chemical production, technology research & development, and import & export. The company focuses on the production, trade, and research & development of various chemical products.
Relying on our wide business channels and professional experience, we are more skillfully providing products of stable but differentiated quality, along with flexible, highly efficient & considerate service to satisfy our partner at more competitive pricing.
Efficiently treating our customers as partners with sincerity, specialization and satisfaction is our managerial principle.
Attributed to the backup of a dedicated technical team, filled with wide and profound knowledge and practice in chemicals and world trade for 20 years, the company owns rich experience in product quality control, technical solution, chemical logistics organization, packaging optimization, port operation, etc., which accounts for its first-class cost control management and ensures to maintain the overwhelming competitive advantage over others.
![]() |
![]() |